Annotation Overview for fig|226186.1.peg.1970 in Bacteroides thetaiotaomicron VPI-5482:
NAD-specific glutamate dehydrogenase (EC 1.4.1.2) / NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
| current assignment |
| |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| taxonomy id | 226186 | contig | ||||||||
| internal links | genome browser | feature evidence | sequence | ACH [?] | show essentially identical genes | |||||||
| PubMed links | 8955404 | |||||||||
| annotation history | run tool | |||||||||
| FigFam | FIG145589 | |||||||||
| data base cross references (dbxref) | ||||||||||
This feature is part of a subsystem
Reasons for Current Assignment
The encoded protein plays multiple roles which are implemented by distinct domains within the
feature. The roles are "NAD-specific glutamate dehydrogenase (EC 1.4.1.2)" and "NADP-specific
glutamate dehydrogenase (EC 1.4.1.4)". The protein occurs in 5 subsystems: "Arginine and Ornithine
Degradation", "Glutamate dehydrogenases", "Glutamine, Glutamate, Aspartate and Asparagine
Biosynthesis", "Proline, 4-hydroxyproline uptake and utilization", and "Proline Synthesis". In
"Arginine and Ornithine Degradation", it appears to play a functional role that we have not
associated with any other gene. In "Glutamate dehydrogenases", it appears to play a functional role
that we have not associated with any other gene. In "Glutamine, Glutamate, Aspartate and Asparagine
Biosynthesis", it appears to play a functional role that we have not associated with any other gene.
In "Proline Synthesis", it appears to play a functional role that we have not associated with any
other gene. The function of this gene is asserted in 8955404.
The function of genes having the same functional roles have been described in Thermotoga maritima
(10366510, 9135121, 9654452, 9680336). This is a homologous protein which implements the same function.
Compare Regions
The chromosomal region of the focus gene (top) is compared with four similar organisms. The graphic is centered on the focus gene, which is red and numbered 1. Sets of genes with similar sequence are grouped with the same number and color. Genes whose relative position is conserved in at least four other species are functionally coupled and share gray background boxes. The size of the region and the number of genomes may be reset. Click on any arrow in the display to refocus the comparison on that gene. The focus gene always points to the right, even if it is located on the minus strand.
